An adhesive (19)F MRI chemical probe allows signal off-to-on-type molecular sensing in a biological environment.

نویسندگان

  • Tomohiro Doura
  • Ryunosuke Hata
  • Hiroshi Nonaka
  • Fuminori Sugihara
  • Yoshichika Yoshioka
  • Shinsuke Sando
چکیده

We report a new strategy for designing a signal off-to-on-type (19)F MRI chemical probe that operates in biological environments. The present strategy is based on the control of adherence of a (19)F MRI chemical probe to certain blood proteins, accompanied by a change in transverse relaxation time of (19)F nuclei.

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عنوان ژورنال:
  • Chemical communications

دوره 49 97  شماره 

صفحات  -

تاریخ انتشار 2013